Is melatonin the Same as 5-HTP?

Is melatonin the Same as 5-HTP?

5-HTP and melatonin are endocrine substances in the body, the main role is to stimulate sleep, diet, etc. But there is a difference between the two, so let's learn more about it below.

5-HTP  is an amino acid substance. It is used in the body as a precursor to 5-HT (5-tryptamine serotonin) (and subsequently as a precursor to melatonin. In some double-blind studies, 5-HTP has been shown to increase brain serotonin concentrations, improve depression, promote melatonin formation, and improve sleep quality.

5-HTP is an important substance that regulates neural activity. It is a powerful and safe natural nutrient that aids sleep and calms the mind. It can produce happy mood messengers that affect almost every aspect of brain activity.
activity, from regulating mood, energy and memory to shaping outlook on life. Effective in improving depression. Insomnia, obesity, etc. There is a wide range of applications in the pet, animal husbandry, aquaculture and other industries.

5-HTP can be converted into serotonin in the body, but serotonin cannot cross the blood-brain barrier to enter the brain, so 5-HTP must first cross the blood-brain barrier and then be converted into serotonin in the brain in order to really play a role in stabilizing mood and promoting sleep quality.

Melatonin is a hormone produced by the pineal gland (located in the middle of the brain) and is called endogenous melatonin. The secretion of melatonin has a circadian rhythm. After nightfall, when light stimulation is reduced, the enzymatic activity of the pineal gland to synthesize melatonin is enhanced and the secretion level of melatonin in the body increases accordingly, reaching a peak at 2-3 a.m. The level of melatonin at night directly affects the quality of sleep.

As we age, the pineal gland atrophy until calcification, resulting in a weakening or loss of biological clock rhythm, especially after the age of 35, the body's own secretion of melatonin decreases significantly, an average of 10-15% per decade, resulting in sleep disorders and a series of dysfunctions, and melatonin levels decrease, sleep reduction is one of the important signs of human brain aging.

5htp is the predecessor of melatonin, and both can be used clinically to treat insomnia. 5htp is a hormone secreted by the brain, and there is a certain amount of it in the body, if less, it can cause anxiety, inability to eat and even depression and insomnia. And melatonin mainly affects people's sleep, at night the human body will secrete a lot of melatonin to promote human sleep. If there is less melatonin in the body, it can also cause insomnia. In the medical field, people can also synthesize 5htp and melatonin for clinical use to help treat insomnia and other symptoms.

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